Metarhizium anisopliae is an entamopathogenic fungi, Which acts a biological insecticide to control many pests or insects such as desert locust, Locusts, Plant hopers, Japanese beetle, Root weevil, Catterpillars, Aphids, Black spittle bugs, Vine weevil, Termites, Cut worms, Thrips, And white grubs etc., By causing green muscardine disease to them. Mechanism of operation metarhizium anisopliae infects insects that come in communication with it. Once the fungus spores attach to the outer outer layer of the insect, They germinate and begin to grow. After penetrating the outside skeleton of they grow, The insect rapidly inside the insect by utilizing the nutrients from insect body, Causing the insect to die. Certain toxins called destruxin produce by this fungus causes mortality of insects.