Nalidixic Acid, CAS Number 389-08-2, Molecular Formula C12H12N2O3

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Synonyms 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt
CAS Number 389-08-2
IUPAC Name 1-Ethyl-7-methyl-4-oxo-[1,8]naphthyridine-3-carboxylic acid
Molecular Formula C12H12N2O3

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Comprehensive Guide to Nalidixic Acid Tablets and Their Applications

Nalidixic acid tradenames nevigramon, Neggram, Wintomylon and win 18, 320 represents the initial of the synthetic quinolone antibiotics. Not a quinolone its, This represents a naphthyridone, In a technical sense ring structure is a 1, 8, Naphthyridine nucleus that contains two nitrogen atoms, Unlike quinoline, That features a single nitrogen atom. 1 synthetic quinolone antibiotics were discovered by george lesher and coworkers as a byproduct of chloroquine manufacture in the 1960s. 1 used clinically from 1967. 1 nalidixic acid is effective primarily with minor, Against gram, Negative bacteria anti, Gram, Positive activity. In lower concentrations, It acts in a that is, Bacteriostatic manner, It inhibits growth and reproduction. In higher concentrations, It is bactericidal, Meaning that it kills bacteria instead of merely inhibiting their growth.

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