Certainly! high molecular weight kininogen hmwk is a 110, Kilodalton single, Chain nonenzymatic cofactor synthesized in the liver. It plays a central role in contact activation reactions. Presenting a selection of details about hmwk function hmwk forms a complex with prekallikrein and factor xi. It links prekallikrein to negatively allowing activation, Charged surfaces to kallikrein by surface, Bound factor, Xiia1. Plasma concentration hmwk s plasma concentration is approximately 70 mg/ml. Plasma half, Life it comes equipped with a plasma half, Life of approximately 144 hours. Coagulation factors hmwk is included in the intrinsic along with, Coagulation pathway factors viii, Ix, Xi, Xii, And prekallikrein. These factors are frequently identified as the contact factors2. If you need further information or have any other questions, Don’t hesitate to ask!